Combined updates from the past of Nanocytronic Phases. Scroll to bottom for latest
1) PHASE 1 UPDATES
side project I started in High school (2021, 2022 - Summer 2023)
- explored advances in connectomics after exposure to Dr. Litchman’s brainbow neuro imaging technique. In particular, I was pursuing better alternatives to volume electron microscopy for super resolution imaging of cells using NEMs and MEMs.
- Most of the “research” I did was self studying, having conversations with experts and taking down notes. It was a side project and merited no experimentation. (Something I regret)
- Also, I preferred writing to typing back then and the side effect is that I have very little to link here of the ideas I explored.
- Ultimately, I shifted from pursuing in-situ cellular manipulation using metamaterials and nanoelectronics to focusing on using proteins and enzymes instead.
Temporary pause (Summer 2023 - Fall 2024.)
Resuming and exploring light sensitive proteins (August 2024)
- Decided to pursue this project full time with the intention of turning it into a proper company that developed advanced tools for currently impossible-to-do bioengineering feats.
- Explored photosensitive rationally designed proteins as potential nano bioengineering agents.
- This was also mostly theory and conversations.
- End goal was a circuit that resembled this 👇
Firing lasers at nm sized micro particles to control their behaviour and in turn the behaviour of cells.
dead end (Summer 2025)
- no nm precision due to light scattering. Even with near field techniques, nm spot size lasers would degrade into multiple um.
- Tweet referencing my struggle months earlier. https://x.com/BagOfNeurons/status/1869727224695550408?s=20
- further investigation & feedback from advisors revealed optical control is a dead end.
Pivot to chemo sensitive NPs and NWs [July 2025]
- Discovering chemo sensitive nanoparticles & nanowire antennas for near field control.
- Checks out theoretically.
2) PHASE 2 UPDATES
- Initial plan was to raise seed round and demonstrate PoC of device later. Pitched a few VCs and got feedback that I needed to demonstrate capability first.
- Found work by Payne et al. 2017, Lieber et al. 2016 and Liao et al. 2019 demonstrating our needed capabilities.
- Got in contact with experimentalists and confirmed key applications. (July 2025)
3) PHASE 3 UPDATES
- Feedback mode (August, September, October, November)
- Conversations with VCs, a CEO of one of the largest biotech companies today and some PIs revealed need for clarity in planned applications of platform.
- Final business model and applications refined to include scientific instrument, nano surgery, and cyberware.
- PHASE 3 initially completed on November 20th 2025, but had to walk back on scientific instrument commercialisation plan.
- Further investigation revealed that resources would only allow for one focus i.e: scientific instrument or in vivo work. In vivo it is.
4) PHASE 4 UPDATES
- coming soon.