Intro to the whole neuron project

A few months ago, I came across a project by Tim Davison called the cell walk app. It is a really cool app that lets you walk through a bacterial cell in 3d and observe the spatial context of its molecules.

This prompted me to try something similar of my own.

What if we had a similar 3d map that allowed us to walk through a neuron?

Right from the membrane on the surface, to the organelles inside of it, to the individual proteins that make up those organelles and everything else.

Well, that is what me and Elijah are trying to do with this project.

Files

• Google drive mega doc ->link
• Render of 3d Base body of ttl5 neuron
• Base body + dendritic spines (Coming soon)
• membrane + membrane structures (Coming soon)
• organelles (soon)

References

1. Galloni AR, Laffere A, Rancz E. Apical length governs computational diversity of layer 5 pyramidal neurons. Elife. 2020 May 28;9:e55761. doi: 10.7554/eLife.55761. PMID: 32463356; PMCID: PMC7334021.
2. Morphological development of thick-tufted layer V pyramidal cells in the rat somatosensory cortex https://doi.org/10.3389/fnana.2011.00005
3. Larkman AU. Dendritic morphology of pyramidal neurones of the visual cortex of the rat: I. Branching patterns. J Comp Neurol. 1991 Apr 8;306(2):307-19. doi: 10.1002/cne.903060207. PMID: 1711057.